KMID : 1037120200380020191
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The World Journal of Men¡Çs Health 2020 Volume.38 No. 2 p.191 ~ p.197
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Validation of SwimCount¢â, a Novel Home-Based Device That Detects Progressively Motile Spermatozoa: Correlation with World Health Organization 5th Semen Analysis
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Yoon Young-Eun
Kim Tae-Yoon Shin Tai-Eun Lee Eun-Ji Choi Kyung-Hwa Lee Seung-Ryeol Hong Young-Kwon Park Dong-Soo Kim Dae-Keun
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Abstract
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Purpose: We evaluated the usefulness of a home-based device (SwimCount¢â) compared with World Health Organization (WHO) 5th semen analysis in screening for male fertility in Asian men.
Materials and Methods: One hundred Asian men who visited CHA Seoul Station Fertility Center for evaluation of fertility were included. Semen samples were analyzed and compared with the SwimCount¢â results. An aliquot of 0.5 mL of the semen sample was added to the SwimCount¢â and a WHO 5th semen analysis was performed. Results were categorized as low (<5¡¿106/mL), and normal to high (¡Ã5¡¿106/mL) total progressively motile sperm concentration. Receiver operating characteristic curve analysis was performed to evaluate the accuracy of the SwimCount¢â.
Results: The mean total progressively motile sperm concentration was 26.7¡¿106/mL. Semen analysis revealed that 28% of the samples were below the threshold count of 5 million/mL total progressively motile sperm concentration. The mean total progressively motile sperm concentration of the light color SwimCount¢â result group determined by semen analysis was 7.5¡¿106/mL, and the mean total progressively motile sperm concentration of the moderate to dark color SwimCount¢â result group was 34.2¡¿106/mL. An area under the receiver operating characteristic curve of 0.85 (95% confidence interval, 0.77?0.94; p<0.001) was obtained when the SwimCount¢â was compared with semen analysis. The sensitivity and specificity were obtained at a cut off value of 5.0¡¿106/mL total progressively motile sperm concentration, giving a sensitivity and specificity of 87.5% and 73.4%.
Conclusions: We confirmed the reliability of the SwimCount¢â as a home-based device for male fertility by evaluating the total progressively motile sperm concentration.
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KEYWORD
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Fertility, Spermatozoa, Sperm count, Sperm motility
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